Abstract: Pharmacological treatment of presbyopia has the potential to become an alternative that is distinct from spectacles and easy to use in the future. At present, there are three main types of drugs - miotic agents, lens softeners and refractive function modulators in the research and development. Miotic agents treat presbyopia by producing a pinhole effect that increases the depth of focus at all working distances. The effects of miotic agents are transient, common adverse events include headache and nocturnal vision loss, and long-term efficacy and safety data are not available. There have been studies in which miotic agents have been used in combination with other drugs to achieve an additive therapeutic effect or to reduce adverse events. However, these combined effects are unknown. The aim of this review is to summarize some recent advances in the pharmacological treatment for presbyopia. (Int Rev Ophthalmol, 2023, 47: 228-232)

Key words: presbyopia, medication